CRISPR Emerged as the Largest Segment for the Global Genome Engineering Market During 2015, says Technavio

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According to the latest market research study released by Technavio, the global genome engineering market is expected to grow at a CAGR of more than 12% during the forecast period 2016-2020.

This market research report by Technavio provides an in-depth analysis of the market in terms of revenue and emerging market trends. The report also includes an up-to-date analysis and forecasts for various market segments and all geographical regions.

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Technavio research analysts categorize the global genome engineering market based on technology:

Global genome engineering market share by technology 2015

 CRISPR

45.15%

 TALEN

23.51%

 ZNF

15.38%

 Antisense Technology

8.62%

 Other Technologies

7.34%



                                                                                  Source: Technavio

The top three revenue contributing product segments are discussed below:

Genome engineering market by CRISPR

The global genome engineering market by CRISPR accounted for more than 45% of total market share in 2015 and is predicted to occupy around 48% of the total market share by 2020. The extensive use of this technology to modify genes that are difficult to manipulate genetically is the primary driver for this market segment. CRISPR is a segment of prokaryotic DNA that contains short base sequence repetition. CRISPR/Cas9 tool is the fastest growing segment in the market and is used for simplified gene editing for various types of cells such as embryo, sperm, and human egg. This tool can modify an organism’s genome permanently, and this modified gene is then transferred from one generation to the other. The primary end-user of this technology are industries like biotechnology and pharmaceutical companies, academic and government research institutes, and contact research organization. Also, the tool is cost effective and user-friendly, which is, in turn, leading to the cumulative demand for this product across various industries.

The vendors are investing in research and development of CRISPR/Cas9 system that will help develop curative therapies for a broad range of disorders. The therapeutic applications of these systems is used to cure any condition, where the underlying molecular pathology is well understood, and it includes genetic disorders, infectious diseases, and cancer. Some other application of this systems includes the use of this technology in living human embryo. This use is expected to improve disease management as it can cure the disease by modifying gene for babies,” says Srinivas Sashidhar, a lead analyst at Technavio for research on life science research tools.

Genome engineering market by TALEN

The global genome engineering market by TALEN accounted for almost 24% of total market share in 2015 and is predicted to occupy around 24% by 2020. This technology is a kind of restriction enzyme that is engineered to cut targeted gene sequences. It helps in correcting human genetic errors that cause a disease and also aid in treating diseases like sickle cell diseases, xeroderma pigmentation, and epidermolysis bullosa. The extensive use of this technology to treat cancer by destroying T-cell receptors will lead to the growth of this market segment. This technology has various applications in end-user industries like biotechnology and pharmaceutical companies. Healthcare institutions are using TALEN also to treat diseases like cystic fibrosis and muscular dystrophy.

Genome engineering market by ZFN      

The global genome engineering market by ZFN accounted for more than 15% of total market share in 2015 and is predicted to occupy around 15% by 2020. The use of this technology to treat disease like HIV, cancer, severe combined immune deficiency, and human X-linked disease will fuel the growth of this market segment. This technology can be used for the generation of gene knockouts in multiple cell lines and creation of knock-in cell lines with promoters, fusion tags or reporters integrated into endogenous genes.

The top leading vendors operating in the global genome engineering market are:

  • GenScript
  • Horizon Discovery Group
  • Integrated DNA Technologies
  • OriGene Technologies

Other prominent vendors in the market include Lonza Group, New England Biolabs, Sangamo Biosciences, Sigma-Aldrich Corporation, Thermo Fisher Scientific, and Transposagen Biopharmaceuticals.

A more detailed analysis is available in the Technavio report titled, ‘Global Genome Engineering Market 2016-2020’. Technavio also customizes reports by other regions and specific segments upon request.

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